For all introductory genetics courses.
Concepts of Genetics emphasises the fundamental ideas of genetics, while exploring modern techniques and applications of genetic analysis. This best-selling text continues to provide understandable explanations of complex, analytical topics and recognises the importance of teaching students how to become effective problem solvers.
The 12th Edition has been extensively updated to provide comprehensive coverage of important, emerging topics such as CRISPR-Cas and the study of posttranscriptional gene regulation in eukaryotes. An expanded emphasis on ethical considerations that genetics is bringing into everyday life is addressed in Genetics, Ethics, and Society and Case Study features.
Part One--Genes, Chromosomes, and Heredity
1 Introduction to Genetics
2 Mitosis and Meiosis
3 Mendelian Genetics
4 Extensions of Mendelian Genetics
5 Sex Determination and Sex Chromosomes
6 Chromosomal Mutations: Variation in Number and Arrangement
7 Chromosome Mapping in Eukaryotes
8 Genetic Analysis and Mapping in Bacteria and Bacteriophages
9 Extranuclear Inheritance
Part Two--DNA: Structure, Replication, and Organization
10 DNA Structure and Analysis
11 DNA Replication and Recombination
12 DNA Organization in Chromosomes
Part Three--Gene Expression and Its Regulation
13 The Genetic Code and Transcription
14 Translation and Proteins
15 Gene Mutation, DNA Repair, and Transposition
16 Regulation of Gene Expression in Bacteria
17 Transcriptional Regulation in Eukaryotes
18 Posttranscriptional Regulation in Eukaryotes
19 Epigenetic Regulation of Gene Expression
Part Four--Genomics
20 Recombinant DNA Technology
21 Genomic Analysis
22 Applications of Genetic Engineering and Biotechnology
Part Five--Genetics of Organisms and Populations
23 Developmental Genetics
24 Cancer Genetics
25 Quantitative Genetics and Multifactorial Traits
26 Population and Evolutionary Genetics
Special Topics in Modern Genetics
ST1 CRISPR and Genome Editing
ST2 DNA Forensics
ST3 Genomics and Precision Medicine
ST4 Genetically Modified Foods
ST5 Gene Therapy
ST6 Advances in Neurogenetics: The Study of Huntington Disease
Appendix A Selected Readings
Appendix B Answers to Selected Problems
